Thin Layer Chromatography

A technique for separating components in a mixture on the basis of their differing polarities.

A spot of sample is placed on a flat sheet coated with silica and then carried along by a solvent that soaks the sheet. Different components will move different distances over the surface.

TLC is a useful screening technique in clinical chemistry; for example, it can be used to detect the presence of drugs in urine.


See also: Chromatography.

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Subjects: Chemistry


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